Extraskeletal actions of vitamin D

Extraskeletal Functions of Vitamin D

1Department of Clinical and Experimental Medicine, University of Messina, Viale Gazzi, 98123 Messina, Italy 2Institute of Molecular BioMedicine, Medical Faculty, Comenius University, Sasinkova 4, 811 08 Bratislava, Slovakia 3Department of Internal Medicine, Service of Nephrology, University Hospital (CHUV), Avenue du Bugnon 17, 1011 Lausanne, Switzerland 4Nephrology, Med School, Second Universi...

Nonclassic actions of vitamin D.

CONTEXT Vitamin D receptors are found in most tissues, not just those participating in the classic actions of vitamin D such as bone, gut, and kidney. These nonclassic tissues are therefore potential targets for the active metabolite of vitamin D, 1,25(OH)(2)D. Furthermore, many of these tissues also contain the enzyme CYP27B1 capable of producing 1,25(OH)(2)D from the circulating form of vitam...

Extraskeletal effects of vitamin D | Rossini | Reviews in Health Care

Minireview: Vitamin D: is there a role in extraskeletal health?

In recent years, vitamin D has received increased attention due to the resurgence of vitamin D deficiency and rickets in developed countries together with the identification of extraskeletal vitamin D receptor-mediated actions, suggesting unexpected benefits of vitamin D in health and diseases. Although there is increased awareness of the importance of vitamin D, the role of vitamin D in extras...

Calcium and vitamin D: skeletal and extraskeletal health.

Vitamin D is known for its role in calcium homeostasis for optimal skeletal health. It was previously believed that only elderly or hospitalized patients were at risk for vitamin D insufficiency, but many people in the general US population have insufficient levels of 25-hydroxyvitamin D (25D). According to the Third National Health and Nutrition Examination Survey, 61% of white and 91% of blac...